If you or your dependent (s) are diagnosed with Hereditary Multiple Osteochondromas and experience any of these symptoms, you may be eligible for disability benefits from the U.S. Social Security Administration. Until the report of Ehrenfried (1) in 1917, mention of this disease was relatively infrequent in the American literature, but since that time numerous cases have been reported (2). Hereditary multiple exostoses (HME) is a rare genetic disorder where several benign cartilaginous tumors arise from the perichondrium and flank the cartilage growth. Learn More. Hereditary multiple osteochondromas (HMO), also called hereditary multiple exostoses, is a genetic disorder that causes the development of multiple, cartilage-covered tumors on the external surfaces of bones (osteochondromas). The bumps can be painful. 1 - 3 This autosomal dominant disease has also been called hereditary multiple osteochondromas, hereditary deforming . Diagnosis is made with radiographs showing sessile or pedunculated lesions . Hereditary multiple osteochondromas (HMO), also called hereditary multiple exostoses, is a genetic disorder that causes the development of multiple, cartilage-covered tumors on the external surfaces of bones ( osteochondromas ). These bumps are noncancerous but can sometimes make it hard to move if they are near the joints. Two EXT genes account for 90% of the lesions. Hereditary Multiple Exostoses: a review of clinical appearance and ... The oral mucosa is the mucous membrane lining the inside of the mouth.It comprises stratified squamous epithelium, termed "oral epithelium", and an underlying connective tissue termed lamina propria. Hereditary Multiple Exostoses - SCOR Global Life Hereditary multiple exostosis- Clinical cases, top doctors Sessile exostoses are permanently attached or fixed and broad, while pedunculated exostoses are connected by a narrow stem. EXT1 and EXT2 have been associated with both familial hereditary exostoses and spontaneous multiple hereditary exostoses.